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Prasugrel Versus Ticagrelor in Patients With CYP2C19 Loss-of-Function Genotypes
Results of a Randomized Pharmacodynamic Study in a Feasibility Investigation of Rapid Genetic Testing Francesco Franchi, MD, Fabiana Rollini, MD, Jose Rivas, MD, Andrea Rivas, MD, Malhar Agarwal, MD, Maryuri…
Pharmacodynamic and Pharmacokinetic Effects of a Low Maintenance Dose Ticagrelor Regimen Versus Standard Dose Clopidogrel in Diabetes Mellitus Patients Without Previous Major Cardiovascular Events Undergoing Elective Percutaneous Coronary Intervention
Footnotes Data sharing: The data, analytic methods, and study materials will not be made available to other researchers for purposes of reproducing the results or replicating the procedure. https://www.ahajournals.org/journal/circDominick J….
Pharmacodynamic and Pharmacokinetic of Switching From Cangrelor to Prasugrel in ACS Patients Undergoing PCI
Overview Cangrelor is an intravenous P2Y12 inhibitor utilized as a bridge to achieve adequate platelet inhibition until oral P2Y12 inhibitors achieve their full antiplatelet effects in patients undergoing coronary stenting….
Scott R. MacKenzie Foundation awards $350,000 in support of two-year clinical trial
Diana Azzam, a researcher in the Robert Stempel College of Public Health & Social Work, will collaborate with Cleveland Clinic Florida on a study to find new treatment options for…
Seeing science fiction become reality
As a child growing up in East Millinocket, Maine, Scott MacKenzie was a huge fan of science and science fiction. One of the first magazines he ever subscribed to was…
Clopidogrel drug interactions: a review of the evidence and clinical implications
ABSTRACT Introduction Patients with cardiovascular disease are commonly affected by a number of comorbidities leading to a high prevalence of polypharmacy. Polypharmacy increases the probability of drug–drug interactions (DDIs). Amongst…
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