Seeing science fiction become reality
As a child growing up in East Millinocket, Maine, Scott MacKenzie was a huge fan of science and science fiction. One of the first magazines…
Clopidogrel drug interactions: a review of the evidence and clinical implications
ABSTRACT Introduction Patients with cardiovascular disease are commonly affected by a number of comorbidities leading to a high prevalence of polypharmacy. Polypharmacy increases the probability…
Evaluating the Extent of Reusability of CYP2C19 Genotype Data among Patients Genotyped for Antiplatelet Therapy Selection
Abstract Purpose. Genotype-guided antiplatelet therapy is increasingly being incorporated into clinical care. The purpose of this study is to determine the extent to which patients…
Acute and Chronic Antithrombotic Therapy in STEMI Patients Undergoing Primary PCI
A review of the anticoagulant and antiplatelet agents currently available for the treatment of STEMI patients undergoing PPCI. Acute ST-segment elevation myocardial infarction (STEMI) comprises…
Mayo Clinic’s Tapestry Study to Collect Genomic Sequencing Data on 100,000 Patients
Initial focus to include familial hypercholesterolemia and hereditary breast and ovarian cancer Collaborating with Helix, a population genomics company, Mayo Clinic said it is creating…
Scientists at MDI Biological Laboratory identify new genetic regulators of regeneration
BAR HARBOR, MAINE — Scientists at the MDI Biological Laboratory and the University of Maine have discovered that genetic material in the cell that was previously thought…
Clinical implementation of rapid CYP2C19 genotyping to guide antiplatelet therapy after percutaneous coronary intervention
Abstract Background The CYP2C19 nonfunctional genotype reduces clopidogrel effectiveness after percutaneous coronary intervention (PCI). Following clinical implementation of CYP2C19 genotyping at University Florida (UF) Health Shands Hospital in…
High School Summer Fellows Participate in Research at MDI Biological Laboratory
Fellowships Offer Opportunity for Real-World Biomedical Research BAR HARBOR, MAINE — Nine high school students participated in research fellowships at the MDI Biological Laboratory in Bar Harbor, Maine,…